Travelling by road:

Travelling from Glasgow:  take the M8 then M80 to Stirling and follow the A9 past Perth to Pitlochry
Travelling  from Edinburgh:  cross the Forth Road Bridge and take the M90 to Perth. Join the A9 to Pitlochry
Travelling  from Dundee:  follow the signs for Perth and Edinburgh. Take the A85 to Perth. Join the A9 to Pitlochry
Travelling from Aberdeen: take the A96, heading towards Inverness. Join the A9 to Pitlochry